ActiMaris AG

Studien

Detailed studies and laboratory reports are available upon request.

Published studies with ActiMaris products:

1. ENT study
   ActiMaris clinical ORL study in inflammatory skin and mucosal processes.
2. Study with acne
   Clinical application observation of a sea salt-oxygen complex for local application.
3. JWC study: Prontosan vs ActiMaris
   A clinical evalutation of the efficacy and safety of singlet oxygen in cleansing and disinfecting stagnating wounds
4. Witten study (in vitro study with 6 HOCl/NaOCl wound products)
   Safety and efficacy profiles of different commercial sodium hypochlorite/hypochlorous acid solutions (NaClO/HClO): antimicrobial efficacy, cytotoxic impact and physicochemical parameters in vitro
5. Antimicrobial in vivo study
   Use of wet-to-moist cleansing nwith different irrigation solutions to reduce bacterial bioburden in chronic wounds
6. Interesting findings
   Restrospective study survey on modern wound irrigation solutions of the HOCl / NaOCl type in daily wound practice.
7. New perspective of an old concept of nature
   The secret of the Rosetta Stone, REDOX Code and the role of HOCl/NaOCl hybrid solutions (data analysis) in local therapy of chronic wounds.
8. Advantages of negative pressure wound therapy
   Advantages of negative pressure wound therapy with instillation of super oxidized solution and dwell time in diabetic foot syndrome: a rare case report

Currently, four clinical randomized comparative studies with ActiMaris products are ongoing:

1. Bioflush – Removal of intestinal biofilms to reduce IBS symptoms, an exploratory randomized, controlled, observer-subject-blinded study.
   (ActiMaris SENSITIVE wound irrigation solution vs. Placebo)
2. Comparative study of two local therapy concepts
   (ActiMaris SENSITIVE wound irrigation solution and ActiMaris woundgel vs. Microdacyn wound irrigation solution and Microdacyn Gel)
3. Utilizzo di antisettici per il trattamento della gengivite in età pediatrica.
   (ActiMaris FORTE vs. clorexidina 0.12%)
4. ActiMaris effectiveness in the evaluation of the ability of sodium hypochlorite solution in bacterial eradication from conteminated cancellus bone.
   Preliminary results show a dramatical reduction in bacterial growth on culture bases, even for the short period of contact between ActiMaris FORTE wound irrigation solution and cancellous bone (with an almost complete absence of growth after 4 minutes.)
5. John Hopkins Evidence-Based Practice Model for Nursing and Healthgare Professionals.
   What is the best practice in improving the healing process of wound among ICU adults and geriatric patients?
   Decubitus / Pressure injury therapy concept with ActiMaris products at the geriatric clinic.
   Emirates Health Services (EHS Dubai) / EBP team. Maitha Ebrahim / Dr. Rania & Ms. Hanane Egli (ActiMaris representative) Goal comletion date: 2nd to 3rd Quarter 2023

Studies planned with ActiMaris products:

1. The USE of ActiMaris Solution and Gel in the Prevention and Treatment of Periodontal Diseases
2. The USE of ActiMaris Solution and Gel during Endodontic Treatment
3. ActiMaris Solution vs. Comparator(s) for Thoracic and Abdominal Lavage during/after Surgery for differnt Infaction Processes and Peritonitis.

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